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Gilead Sciences Inc. (NASDAQ:GILD) recently released that it has submitted a NDA to the U.S. Food and Drug Administration (FDA) for an investigational, once-daily single tablet regimen that combines Gilead’s emtricitabine 200 mg and tenofovir alafenamide (TAF) 25 mg with rilpivirine 25 mg (R/F/TAF) from Janssen Sciences Ireland UC. One of the Janssen Pharmaceutical firms of Johnson & Johnson, for the treatment of HIV-1 infection in adult and pediatric patients 12 years of age and older. The data submitted in the NDA support the use of R/F/TAF among patients who are HIV treatment-naïve or who are virologically suppressed and want to replace their current antiretroviral treatment regimen. TAF is a novel, investigational nucleotide reverse transcriptase inhibitor (NRTI) that has demonstrated high antiviral efficacy at a dose less than one-tenth that of Gilead’s Viread (tenofovir disoproxil fumarate, TDF), as well as improved renal and bone laboratory parameters as compared to TDF in clinical trials in combination with other antiretroviral agents. Shares of Gilead Sciences Inc. (NASDAQ:GILD) opened at $116.33 with 1469.61 million outstanding shares and hit to its highest price of $116.49 during the day and finally closed at $115.04 by scoring -0.84%. In the whole session, it traded on volume of 8.82 Million shares, which turned higher than its average volume.
Teva Pharmaceutical Industries Limited (NYSE:TEVA) released that launch of generic Aggrenox (aspirin/extended-release dipyridamole) capsules in the U.S. Aspirin as well as extended-release dipyridamole capsules are utilized to lower the risk of stroke in people who have had a mini-stroke (transient ischemic attack or TIA) or stroke because of a blood clot. A stroke is reasoned at what time there is an interruption to the flow of oxygen rich blood to the brain. Without oxygen, brain cells can turn out to be damaged and die. Sudden bleeding in the brain can as well reason a stroke if it damages brain cells. A stroke can result in brain damage, long-term disability, or even death. Aspirin and extended-release dipyridamole capsules are indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis. On the other consideration, Teva Pharmaceutical Industries Limited (NYSE:TEVA) begun last trade with a price of $60.95 and throughout the trading session climbed at $61.62. The day-trade ended with a gain of 1.00% to close at $61.56.
Brazilian meat giant, JBS S.A. ADR (OTCMKTS:JBSAY) Pork has signed into an contract with Cargill to purchase the firm’s U.S.-based pork business for $1.45B. Completion of the takeover is subject to regulatory review as well as approval. The firm in JBS’ takeover of Cargill’s pork business are two Midwest meat processing plants, one in Ottumwa, Iowa, and the other at Beardstown, Ill. Cargill acquired both plants in 1987, and in 2014 they processed a total of 9.3 million hogs. The purchase by JBS also includes five feed mills (two in Missouri, and one each in Arkansas, Iowa and Texas), and four hog farms (two in Arkansas and one each in Oklahoma and Texas).